Loading…
MedFuse 2018 has ended
While innovation in the medical space can be daunting or challenging, MedFuse will be a place where both seasoned experts and aspiring talent are welcome together. Not only are there many ways in which the medical field stands to benefit from new perspectives, but there are also many tangential fields to medicine that innovations present in other IoT solutions can serve with fewer barriers. Fields like home monitoring, health and wellness apps, or wearable devices. So if you or your company have ideas, are looking for ideas, or just want to be inspired, MedFuse is the place to come tap into a network of innovators, thinkers, but most importantly, doers. So whether or not you are a trained medical professional, MedFuse is right for you.
Back To Schedule
Tuesday, October 30 • 3:00pm - 3:30pm
Ultrasound Stimulation of Peripheral Nerves and End-Organs for Treating Health Disorders LIMITED

Sign up or log in to save this to your schedule, view media, leave feedback and see who's attending!

Feedback form is now closed.
Limited Capacity seats available

Recently, there has been a surge in interest and efforts towards modulating peripheral nerves (e.g., vagus nerve and trigeminal nerve) and end-organs to treat various health conditions including tinnitus, rheumatoid arthritis, inflammatory bowel disease, depression, and several other diseases. New neurostimulation technologies to access these targets span both invasive and noninvasive devices. Invasive approaches enable more localized stimulation of targets but require surgery and long-lasting miniaturized devices for implantation. Noninvasive approaches do not require surgery and can potentially be distributed to a larger patient population with lower costs but have not yet achieved focused activation of targeted structures. A new modality using ultrasound may enable both noninvasive and targeted stimulation for the treatment of various health disorders.

I will present our experimental findings demonstrating that ultrasound stimulation can enhance or suppress ongoing nerve activity depending on the selected parameters. These neuromodulatory effects may involve both thermal and mechanical mechanisms. Encouragingly, specific parameters of ultrasound stimulation of the spleen also significantly improve inflammatory arthritis in mice. Greater therapy was possible with certain intensities and durations. Combined with published literature, our therapeutic effects are likely mediated via the cholinergic anti-inflammatory pathway through the spleen. These recent findings open up new opportunities for using ultrasound stimulation as a noninvasive approach not only for studying the physiology of the body but also for treating various health disorders involving dysfunction in peripheral nerve activity and/or end-organs.

Speakers
avatar for Dr. Hubert Lim

Dr. Hubert Lim

Associate Professor of Biomedical Engineering, University of Minnesota
Hubert Lim is an Associate Professor in the Biomedical Engineering and Otolaryngology Departments at the University of Minnesota and was hired as an Institute for Translational Neuroscience Scholar. He is also serving as Chief Scientific Officer of Neuromod Devices Limited (Dublin... Read More →


Tuesday October 30, 2018 3:00pm - 3:30pm CDT
CMU 326 Coffman Union 300 Washington Ave SE, Minneapolis, MN 55455